Lansoprazole is a proton pump inhibitor (PPI) medication that is used to treat conditions related to excess stomach acid, such as gastroesophageal reflux disease (GERD), ulcers, and Zollinger-Ellison syndrome. It works by reducing the production of acid in the stomach, which can help relieve symptoms like heartburn and acid reflux.

Lansoprazole is typically taken orally, either as a capsule or as an orally disintegrating tablet. It is available both as a brand-name medication under the trade name Prevacid and as a generic. It has been proven effective in clinical trials and is widely used by healthcare providers to manage a range of gastrointestinal conditions related to excess stomach acid.

As with all medications, it's important to follow the dosing instructions and any additional guidance provided by your healthcare provider to ensure its safe and effective use. If you have any concerns or questions about Lansoprazole, it's important to discuss them with your healthcare provider.

Usage

Lansoprazole is used to treat conditions related to excess stomach acid such as gastroesophageal reflux disease (GERD), ulcers, and Zollinger-Ellison syndrome. It works by reducing the production of acid in the stomach, which helps relieve symptoms like heartburn and acid reflux.

Dosage

The recommended lansoprazole dosage will depend on the individual's condition being treated and other factors. As per search result [1], for the treatment of duodenal ulcer, a usual adult dose of 15 mg orally once per day for up to 4 weeks is recommended. For maintenance, 15mg once daily is recommended. For gastric ulcer, 30 mg orally once per day for 8 weeks is recommended. The dosage may be adjusted by a healthcare provider if necessary.

Side Effects

Lansoprazole may cause some side effects, though not everyone who takes the medication will experience them. Some common side effects of lansoprazole include headache, diarrhea, stomach pain, and nausea. These side effects usually resolve on their own and do not require medical attention.

Less common side effects may include dizziness, fatigue, blurred vision, joint pain, and allergic reactions. It's important to seek medical attention if you experience any severe or persistent side effects, or if you have any concerns about the safety or effectiveness of the medication.

As with all medications, it's important to discuss any potential side effects with your healthcare provider before taking lansoprazole. They can provide guidance on how to use the medication safely and effectively and help you manage any side effects or adverse reactions that may occur.

Precaution

One important precaution for lansoprazole is that long-term use (over three months) may be associated with an increased risk of bone fractures, particularly in the hip, wrist, and spine. This risk may be greater for individuals who are over 50 years old, have a history of osteoporosis, or who take high doses of the medication.

Overdose

An overdose of Lansoprazole may cause symptoms such as confusion , drowsiness, blurred vision, rapid heartbeat, nausea, vomiting, and sweating. If you suspect that you or someone else may have taken too much of this medication, seek emergency medical attention or contact your local Poison Control Center right away.

Interaction

Lansoprazole may interact with other medications, so it's important to let your healthcare provider know about any other medications or supplements you are taking before starting treatment with lansoprazole. Some common medications that may interact with lansoprazole include atazanavir, clopidogrel, and digoxin.

Additionally, lansoprazole may increase the blood levels of certain medications, such as warfarin, methotrexate, and tacrolimus, potentially increasing the risk of adverse effects.

Mechanisms

Lansoprazole works by decreasing gastric acid secretion by selectively targeting H+,K+-ATPase, which is the enzyme that catalyzes the final step in the acid secretion pathway in gastric parietal cells. This leads to a reduced production of gastric acid, which can help treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison Syndrome.

Additionally, research has suggested that lansoprazole may have other mechanisms of action beyond its acid suppression properties. Some studies have investigated lansoprazole's potential anti-inflammatory, anti-tumor, and neuroprotective effects. However, further research is necessary to fully understand these additional mechanisms of action.

If you have any other questions about lansoprazole, you should speak with your healthcare provider. They can provide guidance on how to use the medication safely and effectively.

Disclaimer

It is important to talk to a healthcare provider or pharmacist about all medications and supplements being taken, to determine whether any interactions may occur. They can advise on the appropriate use and dosage of aspirin to avoid any potential drug interactions.