Usage

• Bromhexine is a medication that aids the body's mucus-clearing processes in the respiratory tract and is used to relieve chest congestion.

• It belongs to a class of drugs called mucolytics, which help break down mucus and make it easier to cough up.

• Bromhexine is commonly added to cough syrups to treat coughs associated with excessive mucus production.

• It helps the body's natural mechanisms to remove inflammation by expelling mucus.

Dosage

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The dosage of bromhexine may vary depending on the specific formulation, age, weight, and medical condition of the individual. It is important to follow the instructions provided by the healthcare professional or the information on the medication label.

According to the manufacturer's recommendations, the dosage of bromhexine is as follows:

• Children 2-5 years old: 4mg per dose, taken twice a day.

• Children over 5 years old to 12 years old: 4mg per dose, taken four times a day.

• Children over 12 years old and adults: 8mg per dose, taken three times a day. The dosage can be increased up to 12mg per dose, taken four times a day, but it is necessary to consult a doctor.

Side Effects

• Common side effects of bromhexine may include irritation of the ear, allergic skin rash, dizziness, headache, nausea, vomiting, diarrhea, difficulty breathing, rash, sweating, and respiratory or throat infections.

• Serious side effects may occur if the individual has a history of gastric ulcers, abdominal pain, kidney problems, or liver problems.

Precaution

• Inform your doctor if you have a history of abdominal issues like ulcers, liver problems, or kidney problems before taking bromhexine.

• It is important to consult a healthcare professional for personalized guidance on the usage, dosage, and potential side effects of bromhexine.

Overdose

• The oral LD50 (lethal dose for 50% of the population) of bromhexine in rats is 6 g/kg.

• Symptoms of accidental overdose with bromhexine may include headache, nausea, vomiting, among others.

• If an overdose is confirmed or suspected, it is important to provide symptomatic treatment and contact poison control services.

Interaction

• There are no known drug interactions with bromhexine.

Mechanism

• Bromhexine works by lowering the viscosity of mucus, making it easier to clear the phlegm from the respiratory tract.

• It is accompanied by a rise in lysosomal activity, which helps in breaking down mucus.

Disclaimer

It is important to talk to a healthcare provider or pharmacist about all medications and supplements being taken, to determine whether any interactions may occur. They can advise on the appropriate use and dosage of aspirin to avoid any potential drug interactions.